Publications

45. Karna, D.; Stilgenbauer, M.; Jonchhe, S.; Ankai, K.; Kawamata, I.; Cui, Y.; Zheng, Y.-R.; Suzuki, Y.; Mao, H. Chemo-mechanical Modulation of Cell Motions Using DNA Nanosprings. Bioconjug. Chem. 2021, 32, 311-317.

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44. Jayawardhana, D.; Stilgenbauer, M.; Datta, P.; Qiu, Z.; Beach, T.; Mckenzie, S.; Bowers, D. J.; Kurokawa, M.; Zheng, Y.-R. Mitochondria-Damaging Fatty Acid-Like Pt(IV) Prodrugs Harnessing CD36 to Overcome Drug Resistance in Ovarian Cancer. Chem. Commun. 2020, 56, 10706-10709.

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43. Datta, P.; Bang, S.; Yue, Z.; Beach, T.; Adjiri, S.; Wang, H.; Bowers, D. J.; Kurokawa, M.; Xiao, H.; Zheng, Y.-R. Liposomal Nanoparticles of a Cholesterol-Tethered Amphiphilic Pt(IV) Prodrug Prolong the Circulation Time In Vivo. Dalton Trans. 2020, 49, 8107-8113.

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42. Lozada, I. B.; Huang, B.; Stilgenbauer, M.; Beach, T.; Qiu, Z.; Zheng, Y.-R.; David E. Herbert Planar, Monofunctional Platinum(II) Anticancer Complexes Based on Benzannulated N-Heterocycle-Containing Multidentate Ligand Frameworks. Dalton Trans. 2020, 49, 6557-6560.

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41. Jayawardhana, D.; Qiu, Z.; Kempf, S.; Wang, H.; Miterko, M.; Bowers, D. J.; Zheng, Y.-R. Dual-Action Organoplatinum Nanoparticles Overcoming Drug Resistance in Ovarian Cancer. Dalton Trans. 2019, 48, 12451-12458.

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40. Stilgenbauer, M.; Jayawardhana, D.; Datta, P.; Yue, Z.; Gray, M.; Nielsen, F.; Bowers, D. J.; Xiao, H.; Zheng, Y.-R. A Spermine-Conjugated Lipophilic Pt(IV) Prodrug Designed to Eliminate Cancer Stem Cells in Ovarian Cancer. Chem. Commun. 2019, 55, 6106.

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39. Wang, H.; Qiu, Z.; Liu, H.; Jayawardhana, D.; Yue, Z.; Daghlas, H.; Bowers, D.J.; Datta, B.; Zheng, Y.-R. Nanoparticles of Metal-Organic Cages Overcoming Drug Resistance in Ovarian Cancer. Front. Chem. 2019, 7:39.

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38. Yue, Z.; Wang, H.; Yiming, Li; Qin, Y.; Lin Xu; Bowers, D. J.; Li, X; Yang, H.-B.; Zheng, Y.-R. Coordination-Driven Self-Assembly of a Pt(IV) Prodrug-Conjugated Supramolecular Hexagon. Chem. Commun. 2018, 54, 731.

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37. Yue, Z.; Wang, H.; Bowers, D. J.; Gao, M.; Stilgenbauer, M.; Nielson, F.; Shelley, J. T.; Zheng, Y.-R. Nanoparticles of Metal-Organic Cages Designed to Encapsulate Platinum-Based Anticancer Agents. Dalton Trans. 2018, 47, 670. 

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36. Xiao, H.; Qi, R.; Li, T.; Awuah, S. G.; Zheng, Y.-R.; Wei, W.; Kang, X.; Song, H.; Wang, Y.; Yu, Y.; Bird, M. A.; Jing, X.; Yaffe, M. B.; Birrer, M. J.; Ghoroghchian, P. P. Maximizing Synergistic Activity When Combining RNAi and Platinum-based Anticancer Agents. J. Am. Chem. Soc. 2017, 139, 3033-3044.

35. Zheng, Y.-R.; Suntharalingam, K.; Bruno, P. M.; Lin, W.; Wang, W.; Hemann, M.; Lippard, S. J. Mechanistic Studies of the Anticancer Activity of an Octahedral Hexanuclear Pt(II) Cage. Inorg. Chimica, Acta, 2016, 452, 125.

34. Czapar, A.; Zheng, Y.-R.; Riddell, I. A.; Shukla, S.; Awuah, S. G.; Lippard, S. J.; Steinmetz, N. F. Tobacco Mosaic Virus Delivery of Phenanthriplatin for Cancer Therapy. ACS Nano, 2016, 10, 2119.

33. Awuah, S. G., Zheng, Y.-R.; Bruno, P. B.; Hemann, M. T.; Lippard, S. J. Platinum(IV) Pro-drug Preferentially targets IDO for Enhanced Cancer Immunotherapy. J. Am. Chem. Soc. 2015, 137, 14854.

32. Miller, M. A.; Zheng, Y.-R.; Gadde, S.; Pfirschke, C.; Zope, H.; Engblom, C.; Kohler, R. H.;  Iwamoto Y.; Yang, K. S.; Askevold, B.; Pittet, M.; Lippard, S. J.; Farokhzad, O. C.; Weissleder, R. Tumor associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nat. Commun. 2015, 6, 8692.

 

31. Suntharalingam, K.; Awuah, S. G.;Bruno, P. M.; Johnstone, T. C.; Wang, F.; Lin, W.; Zheng, Y.-R.; Page, J. E.; Hemann, M. T.; Lippard, S. J. Necroptosis-Inducing Rhenium (V) Oxo Complexes. J. Am. Chem. Soc. 2015, 137, 2967-2974.

 

30. Zheng, Y.-R.; Suntharalingam, K.; Johnstone, T. C.; Lippard, S. J. Encapsulation of Pt(IV) Prodrugs within a Pt(II) Cage for Drug Delivery. Chem. Sci. 2015, 6, 1189-1193.

29. Suntharalingam, K.; Lin, W.; Johnstone, T.; Bruno, P.; Zheng, Y.-R.; Hemann, M.; Lippard, S. J. A Breast Cancer Stem Cell-Selective, Mammospheres-Potent Osmium(VI) Nitrido Complex. J. Am. Chem. Soc. 2014, 136, 14413-14416.

 

28. Zheng, Y.-R.; Suntharalingam, K.; Johnstone, T. C.; Yoo, H.; Lin, W.;  Brooks, J. G.; Lippard, S. J. Pt (IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery. J. Am. Chem. Soc. 2014, 136, 8790-8798.

 

27. Cook, T. R.; Zheng, Y.-R.; Stang, P. J. Metal–Organic Frameworks and Self-Assembled Supramolecular Coordination Complexes: Comparing and Contrasting the Design, Synthesis, and Functionality of Metal–Organic Materials. Chem. Rev. 2013, 113, 734-777.

 

26. Zheng, Y.-R.; Lan, W.-J.; Wang, M.; Cook, T. R. Stang, P. J. Designed Post-Self-Assembly Structural and Functional Modifications of a Truncated Tetrahedron. J. Am. Chem. Soc. 2011, 133, 17045–17055.

25. Zheng, Y.-R.; Wang, M.; Kobayashi, S.; Stang, P. J. Self-Assembly of Coordinative Supramolecular Polygons with Open Binding Sites. Tetrahedron Lett. 2011, 52, 2188-2191.

 

24. Wang, M.; Lan, W.-J.; Zheng, Y.-R.; Cook, T. R.; White, H. S.; Stang, P. J. Post-Self-Assembly Covalent Chemistry of Discrete Multicomponent Metallosupramolecular Hexagonal Prisms. J. Am. Chem. Soc. 2011, 133, 10752–10755.

 

23. Wang, M.; Zheng, Y.-R.; Cook, T. R.; Stang, P. J. Construction of Functionalized Metallosupramolecular Tetragonal Prisms via Multicomponent Coordination-Driven Self-Assembly. Inorg. Chem. 2011, 50, 6107–6113.

 

22. Wang, M.; Vajpayee, V.; Shanmugaraju, S.; Zheng, Y.-R.; Zhao, Z.; Kim, H.; Mukherjee, P. S.; Chi, K.-W; Stang. P. J. Coordination-Driven Self-Assembly of M3L2 Trigonal Cages from Pre-organized Metalloligands Incorporating Octahedral Metal Centers and Fluorescent Detection of Nitroaromatics. Inorg. Chem. 2011, 50, 1506-1512.

 

21. Zheng, Y.-R.; Zhao, Z; Wang, M.; Ghosh, K.; Pollock, J. B.; Cook, T. R.; Stang, P. J. A Facile Approach toward Multicomponent Supramolecular Structures: Selective Self-Assembly via Charge Separation. J. Am. Chem. Soc. 2010, 132, 16873–16882.

 

20. Zheng, Y.-R.; Zhao, Z.; Kim, H.; Wang, M.; Ghosh, K.; Pollock, J. B.; Chi, K.-W.; Stang, P. J. Coordination-Driven Self-Assembly of Truncated Tetrahedra Capable of Encapsulating 1,3,5-Triphenylbenzene. Inorg. Chem. 2010, 49, 10238–10240.

19. Zheng, Y.-R.; Ghosh, K.; Yang, H.-B.; Stang, P. J. Coordination-Driven Self-Assembly of Three-Dimensional Supramolecular Dendrimers. Inorg. Chem. 2010, 49, 4747–4749.

 

18. Wang, M.; Zheng, Y.-R.; Ghosh, K.; Stang, P. J. Metallosupramolecular Tetragonal Prisms via Multicomponent Coordination-Driven Template-Free Self-Assembly. J. Am. Chem. Soc. 2010, 132, 6882–6883.

 

17. Zhao, Z.; Zheng, Y.-R.; Wang, M.; Pollock, J. B.; Stang, P. J. Construction of Hexagonal Prisms of Variable Size via Coordination-Driven Multicomponent Self-Assembly. Inorg. Chem. 2010, 49, 8653–8655.

 

16. Xu, X.-D.; Yang, H.-B.; Zheng, Y.-R.; Ghosh, K.; Lyndon, M. M.; Muddiman, D. C.; Stang, P. J. Self-Assembly of Dendritic Tris(crown ether) Hexagons and Their Complexation with Dibenzylammonium Cations . J. Org. Chem. 2010, 75, 7073–7380.

 

15. Zhao, G.-Z.; Chen, L.-J.; Wang, C.-H.; Yang, H.-B.; Ghosh, K.; Zheng, Y.-R.; Lyndon, M. M.; Muddiman, D. C.; Stang, P. J. Facile Self-Assembly of Dendritic Multiferrocenyl Hexagons and Their Electrochemistry. Organometallics 2010, 29, 6137–6140.

 

14. Zheng, Y.-R.; Stang, P. J. Direct and Quantitative Characterization of Dynamic Ligand Exchange between Coordination-Driven Self-Assembled Supramolecular Polygons. J. Am. Chem. Soc. 2009, 131, 3487–3489.

 

13. Zheng, Y.-R.; Yang, H.-B.; Ghosh, K.; Zhao, L.; Stang, P. J. Multicomponent Supramolecular Systems: Self-Organization in Coordination-Driven Self-Assembly. Chem.-Eur. J. 2009, 15, 7203–7214.

 

12. Zheng, Y.-R.; Northrop, B. H.; Yang, H.-B.; Zhao, L.; Stang, P. J. Geometry Directed Self-Selection in Coordination-Driven Self-Assembly of Irregular Supramolecular Polygons. J. Org. Chem. 2009, 74, 3554–3557.

 

11. Northrop, B. H.; Zheng, Y.-R.; Chi, K.-W.; Stang, P. J. Self-Organization in Coordination-Driven Self-Assembly. Acc. Chem. Res. 2009, 42, 1554–1563.

 

10. Zhao, L.; Ghosh, K.; Zheng, Y.-R.; Stang, P. J. Construction of Endo-Functionalized Two Dimensional Metallacycles via Coordination-Driven Self-Assembly. J. Org. Chem. 2009, 74, 8516–8521.

 

9. Zhao, L.; Ghosh, K.; Zheng, Y.-R.; Lyndon, M. M.; Williams, T. I.; Stang, P. J. Construction of Coordination-Driven Self-Assembled [5 + 5] Pentagons Using Metal-Carbonyl Dipyridine Ligands. Inorg. Chem. 2009, 48, 5590–5592.

 

8. Yang, H.-B.; Northrop, B. H.; Zheng, Y.-R.; Ghosh, K.; Stang, P. J. Facile Self-Assembly of Neutral Dendritic Metallocycles via Oxygen-to-Platinum Coordination. J. Org. Chem. 2009, 74, 7067–7074.

 

7. Xu, C.-H.; Sun, W.; Zheng, Y.-R.; Fang, C.-J.; Zhou, C.; Jin, J.-Y.; Yan, C.-H. Logic circuits constructed with an ion-sensitive fluorescent molecule 1,2-di[5-methoxy-2-(2-pyridyl) thiazoyl] ethyne. New J. Chem. 2009, 33, 838–846.

 

6. Yang, H.-B.; Northrop, B. H.; Zheng, Y.-R.; Ghosh, K.; Lyndon, M. M.; Muddiman, D. C.; Stang, P. J. Synthesis of Six-Component Metallodendrimers via [3+3] Coordination-Driven Self-Assembly. J. Org. Chem. 2009, 74, 3524–3527.

 

5. Zheng, Y.-R.; Yang, H.-B.; Northrop, B. H.; Ghosh, K.; Stang, P. J. Size Selective Self-Sorting in Coordination-Driven Self-Assembly of Finite Ensembles. Inorg. Chem. 2008, 47, 4706–4711.

 

4. Zhao, L.; Northrop, B. H.; Zheng, Y.-R.; Yang, H.-B.; Lee, H. J.; Lee, Y. M.; Park, J. Y.; Chi, K.-W.; Stang, P. J.  Self-Selection in the Self-Assembly of Isomeric Supramolecular Squares from Unsymmetrical Bis(4-pyridyl)acetylene Ligands. J. Org. Chem. 2008, 73, 6580–6586.

 

3. Ghosh, K.; Yang, H.-B.; Northrop, B. H.; Lyndon, M. M.; Zheng, Y.-R.; Muddiman, D. C.; Stang, P. J. Coordination-Driven Self-Assembly of Cavity-Cored Multiple Crown Ether Derivatives and Poly[2]pseudorotaxanes. J. Am. Chem. Soc. 2008, 130, 5320–5334.

 

2. Sun, W.; Zheng, Y.-R.; Xu, C.-H.; Fang, C.-J.; Yan, C.-H. Fluorescence-Based Reconfigurable and Resettable Molecular Arithmetic Mode. J. Phys. Chem. C 2007, 111, 11706–11711.

 

1. Yang, H.-B.; Ghosh, K.; Northrop, B. H.; Zheng, Y.-R.; Lyndon, M. M.; Muddiman, D. C.; Stang, P. J. A Highly Efficient Approach to the Self-Assembly of Hexagonal Cavity-Cored Tris[2]pseudorotaxanes from Several Components via Multiple Noncovalent Interactions. J. Am. Chem. Soc. 2007, 129, 14187–14189.